# Enable DSUR and PBRER Investigational Product Causality

Learn how to configure your Vault to only consider causal assessments related to Investigational Products in the DSUR and PBRER.

## About the Feature

With the 23R2 release, you can configure your Safety Vault to consider only _Case Assessment Results_ for _Study Products_ that are blinded or have a _Study Product Role_ of _Investigational_, _Placebo_, or _Active Comparator_ when deciding if a _Case_ should be included in the DSUR and PBRER Serious Adverse Reaction listings and tabulations. For any applicable _Study Product_, Vault includes the _Case_ if the _Causality Established_ field is set to _Yes_ or is blank. Previously, Vault considered all assessments for causality and all adverse event counts to determine if a _Case_ should be included in the Serious Adverse Reaction listings.

### 24R1 Update: DSUR and PBRER: Cumulative Tabulations for all IMP, Comparator, Placebo and Blinded Case Study Products

With the 24R1 release, Vault extends this feature to the Cumulative Tabulation of Serious Adverse Events when determining the appropriate column for case counting. In addition, when this feature is enabled, Vault considers all the _Study Products_ on the _Case_, not just the primary _Case Product_.

For more information, see:

* <a href="/en/gr/01280/#causality-established-is-yes-or-blank-on-any-case-assessment">Create DSUR Aggregate Reports</a>
* <a href="/en/gr/01282/#causality-established-is-yes-or-blank-on-any-case-assessment">Create PBRER Aggregate Reports</a>
* <a href="/en/gr/840364/">Investigational Product Causality on SAE Tabulations (DSUR and PBRER)</a>

## Configure the Aggregate Report Settings

To enable this feature for DSUR and PBRER, complete the following steps.

1. Go to **Admin > Settings > Aggregate Report Settings**.
2. Select **Edit** and then select the **Only Include Investigational Products for SAR** checkbox.
3. Select **Save**.