# Enable Signal Management

With the 23R2 release, SafetyDocs supports <a href="/en/lr/01243/">signal management</a>, offering the ability to track signals as _Product-Event Combinations_, set _PEC Periods_, and record details of _Safety Investigations_.

## Overview

To configure this feature in your Vault:
* [Configure object layouts][1]
* [Configure the _Reporting Period_ field on the _Safety Investigation_ object][7]
* [Configure object workflows][8]
* [Configure object lifecycles][11]
* [Configure security][15]

## Configure Layouts {#object-layouts}

Configure the following object layouts:

* [_Product-Event Combination_][2]
* [_PEC Period_][3]
* [_Signal Source_][4]
* [_Safety Investigation_][5]
* [_Safety Investigation Reporting Period_][6]

### Configure the Product-Event Combination Object Layout {#product-event-combination-object-layout}

To configure the _Product-Event Combination_ object layout: 

1.  Navigate to **Admin > Configuration > Objects > Product-Event Combination > Layouts > Product-Event Combination Detail Page Layout**.
2.  Drag the **Primary MedDRA Term** field from the _Details_ section into the _System_ section.
3.  To the _Details_ section, <a href="/en/lr/26387/#how-to-add-object-fields">add</a> the <img class="inline" src="https://platform.veevavault.help/assets/images/saf-app-control.png" alt="Slider" style="" /> **Primary MedDRA Term** control field with the slider icon.
4.  Configure the rest of the object layout as follows:
    * Ensure the _Details_ section contains the following fields in the following order:
        * _Primary Product Family_
        * <img class="inline" src="https://platform.veevavault.help/assets/images/saf-app-control.png" alt="Slider" style="" /> _Primary MedDRA Term_
        * _Most Recent Disposition_
        * _Most Recent Disposition Date_
    * Ensure the _Product-Event Dispositions_ section contains the following default columns in the following order:
        * _Name_
        * _Detection Date_
        * _Reporting Period_
        * _Primary Source_
        * _Final Disposition_
        * _Final Disposition Date_
        * _Investigation Type_
        * _Safety Investigation_
    * Ensure the _System_ section contains the following fields in the following order:
        * _Combination Name_
        * _Created By_
        * _Created Date_
        * _Primary MedDRA Term_
        * _Last Modified By_
        * _Last Modified Date_
    * Ensure the _Documents_ section contains the following columns in the following order:
        * _Name_
        * _Document Number_
        * _Created By_
        * _Created Date_
    * Ensure there is a _Workflow Timeline_ section
5.  Select **Save**.

### Configure the PEC Period Object Layout {#pec-period-object-layout}

To configure the _PEC Period_ object layout:

1.  Navigate to **Admin > Configuration > Objects > PEC Period > Layouts > PEC Period Detail Page Layout**.
2.  To the _Details_ section, <a href="/en/lr/26387/#how-to-add-object-fields">add</a> the <img class="inline" src="https://platform.veevavault.help/assets/images/saf-app-control.png" alt="Slider" style="" /> **Primary MedDRA Term** control field with the slider icon.
4.  Configure the rest of the object layout as follows:
    * Ensure the _Details_ section contains the following fields in the following order:
        * _Product-Event Combination_
        * _Primary Product Family_
        * <img class="inline" src="https://platform.veevavault.help/assets/images/saf-app-control.png" alt="Slider" style="" /> _Primary MedDRA Term_
        * _Primary Source_
        * _Reporting Period_
        * _Investigation Type_
        * _Detection Date_
        * _Final Disposition_
        * _Final Disposition Date_
        * _Safety Investigation_
    * Ensure the _Documents_ section contains the following columns in the following order:
        * _Name_
        * _Document Number_
        * _Type_
        * _Subtype_
        * _Classification_
        * _Status_
    * Ensure there is a _Workflow Timeline_ section
    * Ensure the _System_ section contains the following fields in the following order:
        * _Created By_
        * _Created Date_
        * _Last Modified By_
        * _Last Modified Date_
5.  Select **Save**.

### Configure the Signal Source Object Layout {#signal-source-object-layout}

To configure the _Signal Source_ object layout:

1.  Navigate to **Admin > Configuration > Objects > Signal Source > Layouts > Signal Source Detail Page Layout**.
2.  Configure the object layout as follows:
    * Ensure the _Details_ section contains the _Name_ field
    * Ensure the _Product-Event Dispositions_ section contains the following default columns in the following order:
        * _Name_
        * _Detection Date_
        * _Final Disposition_
        * _Final Disposition Date_
        * _Reporting Period_
        * _Safety Investigation_
        * _Investigation Type_
        * _Primary Product Family_
    * Ensure there is a _Workflow Timeline_ section
    * Ensure the _System_ section contains the following fields in the following order:
        * _Created By_
        * _Created Date_
        * _Last Modified By_
        * _Last Modified Date_
3.  Select **Save**.

### Configure the Safety Investigation Object Layout {#safety-investigation-object-layout}

To configure the _Safety Investigation_ object layout:

1.  Navigate to **Admin > Configuration > Objects > Safety Investigation > Layouts > Safety Investigation Detail Page Layout**.
2.  Configure the object layout as follows:
    * Ensure the _Details_ section contains the following fields in the following order:
        * _Product Family_
        * _Primary Source_
        * _Start Date_
        * _Detection Date_
        * _Priority_
        * _Validation Outcome_
        * _Validation Outcome Date_
        * _Final Disposition_
        * _Final Disposition Date_
    * Ensure there is a _Workflow Timeline_ section
    * Ensure the _Product-Event Dispositions_ section contains the following default columns in the following order:
        * _Name_
        * _Detection Date_
        * _Final Disposition_
        * _Final Disposition Date_
        * _Reporting Period_
        * _Safety Investigation_
        * _Investigation Type_
        * _Primary Product Family_
    * Ensure the _Summary of Key Data_ section includes the _Summary of Key Data_ field
    * Ensure the _Documents_ section contains the following columns in the following order:
        * _Name_
        * _Document Number_
        * _Type_
        * _Subtype_
        * _Classification_
        * _Status_
    * Ensure the _System_ section contains the following fields in the following order:
        * _Created By_
        * _Created Date_
        * _Last Modified By_
        * _Last Modified Date_
3.  Select **Save**.

### Configure the Safety Investigation Reporting Period Object Layout {#safety-investigation-reporting-period-object-layout}

To configure the _Safety Investigation Reporting Period_ object layout:

1.  Navigate to **Admin > Configuration > Objects > Signal Reporting Period > Layouts > Safety Investigation Reporting Period Detail Page Layout**.
2.  Configure the object layout as follows:
    * Ensure the _Details_ section contains the following fields in the following order:
        * _Name_
        * _Product Family_
        * _Start Date_
        * _End Date_
    * Ensure the _Product-Event Dispositions_ section contains the following default columns in the following order:
        * _Name_
        * _Detection Date_
        * _Final Disposition_
        * _Final Disposition Date_
        * _Reporting Period_
        * _Safety Investigation_
        * _Investigation Type_
        * _Primary Product Family_
    * Ensure the _Safety Investigations_ section contains the following default columns in the following order:
        * _Name_
        * _Detection Date_
        * _Final Disposition_
        * _Final Disposition Date_
        * _Product Family_
        * _Reporting Period_
        * _Validation Outcome_
    * Ensure there is a _Workflow Timeline_ section
    * Ensure the _System_ section contains the following fields in the following order:
        * _Created By_
        * _Created Date_
        * _Last Modified By_
        * _Last Modified Date_
3.  Select **Save**.

## Configure the Reporting Period Field {#reporting-period-field}

To configure the _Reporting Period_ field on the _Safety Investigation_ object:

1. Navigate to **Admin > Configuration > Objects > Safety Investigation > Fields**.
2. Select **Reporting Period**.
3. Select **Edit**.
4. Clear the **Display in default lists and hovercards** checkbox.
5. Select **Save**.

## Configure Object Workflows {#object-workflows}

Configure signal management <a href="/en/lr/33498/">object workflows</a>. Use these steps as a starting point, but configure your workflows according to your business processes:

* [_Safety Investigation Workflow_][9]
* [_Evaluate Disposition Workflow_][10]

### Create the Safety Investigation Workflow {#safety-investigation-workflow}

To create the _Safety Investigation Workflow_:

1.  Navigate to **Admin > Configuration > Workflows**.
2.  Select **Create**.
3. In the _Create Workflow_ window, select **Object Workflow**.
4. Select **Continue**.
5. On the _Create Workflow_ page, populate the fields as follows:
    * **Label**: Enter `Safety Investigation Workflow`
    * **Lifecycle**: Select **Safety Investigation Lifecycle**
6. Select **Save**.
7. In the _Workflow Steps_ section, configure the workflow to include the following steps:
    * _Start_ <a href="/en/lr/33550/#start">start step</a>
    * _Add Role_ <a href="/en/lr/33550/#how-to-define-an-update-sharing-settings-step">update sharing settings step</a>
    * _SC: Triage_ state change <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _Task: Prioritize_ <a href="/en/lr/33550/#wftaskstep">task step</a>
    * _Decision: Pass Validation?_ <a href="/en/lr/33550/#decision">decision step</a>
    * _SC: In Progress_ state change <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _Task: Further Assessment_ <a href="/en/lr/33550/#wftaskstep">task step</a>
    * _Decision: Reg Review?_ <a href="/en/lr/33550/#decision">decision step</a>
    * _Set Refuted_ <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _SC: Regulatory Review_ state change <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _Task: Coordinate Regulatory Review_ <a href="/en/lr/33550/#wftaskstep">task step</a>
    * _Decision: Reg Review Outcome_ <a href="/en/lr/33550/#decision">decision step</a>
    * _SC: Mitigation_ state change <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _SC: Continue Monitoring_ state change <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _SC: Closed_ state change <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _End_ <a href="/en/lr/33550/#how-to-define-an-end-workflow-step">end step</a>
8. In the **Status** field, select **Make configuration active**.

<a href="https://platform.veevavault.help/assets/images/saf-23r2-signal-mgmt-workflow.png" data-lightbox="saf-23r2-signal-mgmt-workflow.png" data-title="Safety Investigation Workflow" data-alt="Safety Investigation Workflow">
  <img class="docimage" src="https://platform.veevavault.help/assets/images/saf-23r2-signal-mgmt-workflow.png" alt="Safety Investigation Workflow" style=""  />
</a>

### Create the Evaluate Disposition Workflow {#evaluate-disposition-workflow}

To create the _Evaluate Disposition Workflow_:

1.  Navigate to **Admin > Configuration > Workflows**.
2.  Select **Create**.
3. In the _Create Workflow_ window, select **Object Workflow**.
4. Select **Continue**.
5. On the _Create Workflow_ page, populate the fields as follows:
    * **Label**: Enter `Evaluate Disposition Workflow`
    * **Lifecycle**: Select **Product-Event Disposition Lifecycle**
6. Select **Save**.
7. In the _Workflow Steps_ section, configure the workflow to include the following steps:
    * _Start_ <a href="/en/lr/33550/#start">start step</a>
    * _Add Role_ <a href="/en/lr/33550/#how-to-define-an-update-sharing-settings-step">update sharing settings step</a>
    * _SC: In Progress_ state change <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _Task: Complete Review_ <a href="/en/lr/33550/#wftaskstep">task step</a>
    * _SC: Complete_ state change <a href="/en/lr/33550/#how-to-define-an-action-step">action step</a>
    * _End_ <a href="/en/lr/33550/#how-to-define-an-end-workflow-step">end step</a>
8. In the **Status** field, select **Make configuration active**.

<a href="https://platform.veevavault.help/assets/images/saf-23r2-signal-mgmt-disposition-workflow.png" data-lightbox="saf-23r2-signal-mgmt-disposition-workflow.png" data-title="Evaluate Disposition Workflow" data-alt="Evaluate Disposition Workflow">
  <img class="docimage" src="https://platform.veevavault.help/assets/images/saf-23r2-signal-mgmt-disposition-workflow.png" alt="Evaluate Disposition Workflow" style=""  />
</a>

## Configure Object Lifecycles {#object-lifecycles}

To configure signal management object lifecycles:

* [Configure actions on the _Safety Investigation Lifecycle_][12]
* [Configure actions on the _Product-Event Disposition Lifecycle_][13]
* [Configure a _Safety Investigation_ _Lifecycle Stage Group_][14]

### Configure Actions on the Safety Investigation Lifecycle {#safety-investigation-lifecycle}

To update the _Safety Investigation Lifecycle_ object lifecycle to support the _Safety Investigation Workflow_, create the following:

<table>
    <thead>
        <tr>
            <th>Lifecycle State</th>
            <th>Type</th>        
            <th>Configuration</th>
        </tr>
    </thead>
    <tbody>
        <tr>
            <td><em>Open</em></td>
            <td><a href="/en/lr/59885/#define-actions">User action</a></td>
            <td>
                <ul>
                  <li><strong>Condition Type</strong>: Select <strong>Always</strong></li>
                  <li><strong>Allow the following actions</strong>:
                    <ul>
                      <li>Select <strong>Workflow</strong></li>
                        <ul>
                          <li>Select <strong>Safety Investigation Workflow</strong></li>
                          <li><strong>Action Label</strong>: Enter <code>Start Investigation</code></li>
                        </ul>
                      <li>Select <strong>Change State to</strong></li>
                        <ul>
                          <li>Select <strong>Closed</strong></li>
                          <li><strong>Action Label</strong>: Enter <code>Close Investigation</code></li>
                        </ul>
                    </ul>
                  </li>
                </ul>
            </td>
        </tr>
        <tr>
            <td><em>Monitoring</em></td>
            <td><a href="/en/lr/59885/#define-actions">User action</a></td>
            <td>
                <ul>
                  <li><strong>Condition Type</strong>: Select <strong>Always</strong></li>
                  <li><strong>Allow the following actions</strong>:
                    <ul>
                      <li>Select <strong>Change State to</strong></li>
                        <ul>
                          <li>Select <strong>Closed</strong></li>
                          <li><strong>Action Label</strong>: Enter <code>Change State to Closed</code></li>
                        </ul>
                      <li>Select <strong>Change State to</strong></li>
                        <ul>
                          <li>Select <strong>Open</strong></li>
                          <li><strong>Action Label</strong>: Enter <code>Re-Open</code></li>
                        </ul>
                    </ul>
                  </li>
                </ul>
            </td>
        </tr>
        <tr>
            <td><em>Closed</em></td>
            <td><a href="/en/lr/59885/#how-to-define-entry-criteria">Entry criteria</a></td>
            <td>
                <ul>
                  <li><strong>Condition Type</strong>: Select <strong>Always</strong></li>
                  <li><strong>Validate that</strong>:</li>
                    <ul>
                      <li>Select <strong>Field</strong> > <strong>Final Disposition</strong> > <strong>is not blank</strong></li>
                      <li>Select <strong>Field</strong> > <strong>Final Disposition Date</strong> > <strong>is not blank</strong></li>
                      <li>Select <strong>Field</strong> > <strong>Validation Outcome</strong> > <strong>is not blank</strong></li>
                    </ul>
                </ul>
            </td>
        </tr>
    </tbody>
</table>

### Configure Actions on the Product-Event Disposition Lifecycle {#product-event-disposition-lifecycle}

To update the _Product-Event Disposition Lifecycle_ object lifecycle to support the _Evaluate Disposition Workflow_, create the following:

<table>
    <thead>
        <tr>
            <th>Lifecycle State</th>
            <th>Type</th>        
            <th>Configuration</th>
        </tr>
    </thead>
    <tbody>
        <tr>
            <td><em>Active</em></td>
            <td><a href="/en/lr/59885/#define-actions">User action</a></td>
            <td>
                <ul>
                  <li><strong>Condition Type</strong>: Select <strong>Always</strong></li>
                  <li><strong>Allow the following actions</strong>:</li>
                    <ul>
                      <li>Select <strong>Workflow</strong></li>
                        <ul>
                          <li>Select <strong>Evaluate Disposition Workflow</strong></li>
                          <li><strong>Action Label</strong>: Enter <code>Evaluate Disposition</code></li>
                        </ul>
                      <li>Select <strong>Change State to</strong></li>
                        <ul>
                          <li>Select <strong>In Progress</strong></li>
                          <li><strong>Action Label</strong>: Enter <code>Change State to In Progress</code></li>
                        </ul>
                      <li>Select <strong>Change State to</strong></li>
                        <ul>
                          <li>Select <strong>Complete</strong></li>
                          <li><strong>Action Label</strong>: Enter <code>Change State to Complete</code></li>
                        </ul>
                    </ul>
                </ul>
            </td>
        </tr>
        <tr>
            <td rowspan="2"><em>Complete</em></td>
            <td><a href="/en/lr/59885/#how-to-define-entry-criteria">Entry criteria</a></td>
            <td>
                <ul>
                  <li><strong>Condition Type</strong>: Select <strong>Always</strong></li>
                  <li><strong>Validate that</strong>: Select <strong>Field</strong> > <strong>Final Disposition</strong> > <strong>is not blank</strong></li>
                </ul>
            </td>
        </tr>
        <tr>
            <td><a href="/en/lr/59885/#define-entry-action">Entry action</a></td>
            <td>
                <ul>
                  <li><strong>Condition Type</strong>: Select <strong>All conditions are met</strong></li>
                  <li><strong>If</strong>: Select <strong>Final Disposition Date</strong> > <strong>is blank</strong></li>
                  <li><strong>perform actions</strong></li>
                    <ul>
                      <li>Select <strong>Update field</strong></li>
                      <li><strong>Fields</strong>: Select <strong>Final Disposition Date</strong></li>
                      <li><strong>Set to value</strong>: Enter <code>today()</code></li>
                    </ul>
                </ul>
            </td>
        </tr>
    </tbody>
</table>

### Configure the Safety Investigation Lifecycle Stage Group {#safety-investigation-lifecycle-stage-group}

Create an <a href="/en/lr/52053/#how-to-create-object-lifecycle-stage-groups">object lifecycle stage group</a> with the following settings:
* **Stage Group Label**: Enter `Safety Investigation Stages`
* **Object Lifecycle**: Select **Safety Investigation Lifecycle**
* **Object Type**: Select **Base Safety Investigation**

Then, create <a href="/en/lr/52053/#how-to-create-stages">stages</a> and define their states as follows:

|Stage|States|
|--- |--- |
|_Signal Prioritization_|_Open_|
|_Signal Validation_|_Triage_, _Regulatory Review_|
|_Further Assessment_|_In Progress_|
|_Mitigation_|_Monitoring_, _Risk Mitigation_|
|_Complete_|_Complete_|

## Configure Security {#security}

Configure security settings to grant access to signal management features. Use the following settings as a starting point, but configure access according to your business processes:

* Create a <a href="/en/lr/22824/">permission set</a> with the label `Signal Management`
* Create a <a href="/en/lr/23647/#how-to-create-new-profiles">security profile</a> with the label `Signal Management` and assign to it the _Signal Management_ permission set
* Create a <a href="/en/lr/3200/#how-to-create-custom-groups">group</a> with the label `Signal Managers` and add the _Signal Management_ security profile as an included security profile
* [Configure permissions for the _Signal Management_ document type][16]
* [Grant permissions on the _Signal Management_ permission set][17]

### Configure Document Type Permissions {#document-type-permissions}

To configure permissions for the _Signal Management (signal\_management\_\_v)_ <a href="/en/lr/618/">document type</a>:

1.  Navigate to **Admin > Configuration > Document Types**.
2.  Select **Signal Management (signal\_management\_\_v)** and then in the **All Actions** menu, select **Edit Details**.
3.  Navigate to the **Security** tab.
4.  In the **Create Document Permission** field, add the following:
    *   **Administrators**
    *   **Signal Managers**
5.  Under _Default Settings for New Documents_, in the **Editors** field, add **Signal Managers**.
6.  Select **Save**.

### Grant Permissions on the Signal Management Permission Set {#signal-management-permission-set}

To grant permissions to the _Signal Management_ permission set:

1. Grant _Read_ <a href="/en/lr/22824/#objectpermissions">object permissions</a> on the following objects:
    *   _Aggregate Reporting Group_
    *   _Case_
        *   _Case_
        *   _Parent Information_
        *   _Imported Case_
        *   _Child Information_
    *   _Case Access Group_
    *   _Case Adverse Event_
    *   _Case Assessment_
    *   _Case Assessment Expectedness_
    *   _Case Assessment Result_
    *   All _Case Cause of Death_ objects
    *   All _Case Contact_ objects
    *   _Case Diagnosis_
    *   _Case Drug History_
    *   _Case Drug History Substance_
    *   _Case Identifier_
    *   _Case Medical History_
    *   _Case Number_
    *   All _Case Product_ objects
    *   _Case Product Device Code_
    *   _Case Product Dosage_
    *   _Case Product Indication_
    *   All _Case Product Registration_ objects
    *   _Case Product Substance_
    *   _Case Relationship_
    *   _Case Signature_
    *   _Case Study Registration_
    *   _Case Test Result_
    *   All _Controlled Vocabulary_ objects
    *   _Country_
    *   _Country State/Province_
    *   _Datasheet_
    *   All _Device Code_ objects
    *   _Dictionary_
        *   _MedDRA Dictionary_
        *   _WHODrug Dictionary_
        *   _EDQM Standard Term_
        *   _IMDRF Device Code_
    *   _Document Lifecycle Stage Label_
    *   _Document Lifecycle State-Stage_
    *   _Document Type Detail_
    *   _Document Type Group_
    *   _Document Type Group Detail_
    *   _Document Usage_
    *   _Dose Form_
    *   _EDQM_
    *   _Emailed Document_
    *   _IMDRF Device Code_
    *   _Inactive Ingredient_
    *   _Inactive Ingredient Registration_
    *   _Inbox Item_
    *   _Language_
    *   _Language (ISO)_
    *   _Language Locale_
    *   _Literature Article_
    *   _Literature Database_
    *   _Literature Review_
    *   _Literature Search Term_
    *   _Local Reporting Details_
    *   _Local Reporting Details/Product Join_
    *   _Locale_
    *   _Localization_
    *   _Localized Case_
    *   _Localized Case Adverse Event_
    *   _Localized Case Assessment_
    *   _Localized Case Assessment Result_
    *   _Localized Case Cause of Death_
    *   _Localized Case Comment_
    *   _Localized Case Contact_
    *   _Localized Case Document_
    *   _Localized Case Drug History_
    *   _Localized Case Identifier_
    *   _Localized Case Medical History_
    *   _Localized Case Product_
    *   _Localized Case Product Device Code_
    *   _Localized Case Product Dosage_
    *   _Localized Case Product Indication_
    *   _Localized Case Product Substance_
    *   _Localized Case Test Result_
    *   _Localized Case Translation_
    *   _Localized Controlled Vocabulary_
    *   _Localized Country_
    *   _Localized Country State/Province_
    *   _Localized Dose Form_
    *   _Localized Organization_
    *   _Localized Product_
    *   _Localized Reason Omitted_
    *   _Localized Route of Administration_
    *   _Localized Study_
    *   _Localized Study Arm_
    *   _Localized Substance_
    *   _Localized Unit of Measurement_
    *   _Market Segment_
    *   _MedDRA_
    *   _MedDRA (Localized)_
    *   _MedDRA Criteria_
        *   _Datasheet Criteria_
        *   _Watchlist Criteria_
        *   _MedDRA Query Criteria_
    *   _MedDRA Join_
    *   _MedDRA Query_
    *   _MedDRA Synonym_
    *   _MedDRA Synonym Context_
    *   _MedDRA Version_
    *   _Object Lifecycle Stage Label_
    *   _Object Lifecycle State-Stage_
    *   All _Organization_ objects
    *   All _Person_ objects
    *   All _Product_ objects
    *   _Product Alias_
    *   _Product Constituent_
    *   _Product Family_
    *   _Product Registration_
    *   _Product Substance_
    *   _Product-Event Combination_
    *   _PEC Period_
    *   _Reason Omitted_
    *   _Report_
    *   _Reporting Group Product Registration_
    *   _Reporting Group Study Registration_
    *   _Safety Investigation_
    *   _Signal Reporting Period_
    *   _Signal Source_
    *   _Study_
    *   _Study Arm_
    *   _Study Arm Product_
    *   _Study Indication_
    *   _Study Person_
    *   All _Study Product_ objects
    *   _Study Product Group_
    *   _Study Product Placeholder_
    *   _Study Product Substance_
    *   _Study Registration_
    *   _Study Site_
    *   _Substance_
    *   _Substance Alias_
    *   _Tab Group_
    *   All _Transmission_ objects
    *   _Unit of Measurement_
    *   All _User Task_ objects
    *   _Validation Result_
    *   _Workflow_
3. Grant _Create_ <a href="/en/lr/22824/#objectpermissions">object permissions</a> on the following objects:
    *   _Product-Event Combination_
    *   _PEC Period_
    *   _Safety Investigation_
    *   _Signal Reporting Period_
    *   _Signal Source_
4. Grant _Edit_ <a href="/en/lr/22824/#objectpermissions">object permissions</a> on the following objects:
    *   _Product-Event Combination_
    *   _PEC Period_
    *   _Safety Investigation_
    *   _Signal Reporting Period_
    *   _Signal Source_
5. Grant _Delete_ <a href="/en/lr/22824/#objectpermissions">object permissions</a> on the _PEC Period_ object.
6. Grant _View_ <a href="/en/lr/22824/#tab-permissions">tab permissions</a> for the _Signal Management_ tab collection and the following tabs: 
    *   _Home_
    *   _Cases_
    *   _Analytics_
        *   _Reports_
        *   _Dashboards_
    *   _Literature_
        *   _Literature Articles_
    *   _Product-Event Combinations_
    *   _Safety Investigations_
    *   _Safety Investigation Reporting Periods_
    *   _Generated PSMFs_

[1]: #object-layouts
[2]: #product-event-combination-object-layout
[3]: #pec-period-object-layout
[4]: #signal-source-object-layout
[5]: #safety-investigation-object-layout
[6]: #safety-investigation-reporting-period-object-layout
[7]: #reporting-period-field
[8]: #object-workflows
[9]: #safety-investigation-workflow
[10]: #evaluate-disposition-workflow
[11]: #object-lifecycles
[12]: #safety-investigation-lifecycle
[13]: #product-event-disposition-lifecycle
[14]: #safety-investigation-lifecycle-stage-group
[15]: #security
[16]: #document-type-permissions
[17]: #signal-management-permission-set