# Enable Auxiliary Medicinal Product Support

Learn how to configure your Vault to support unauthorized Auxiliary Medicinal Products (AxMPs).

## About the Feature

With the 25R1 release, Vault provides the ability to generate the CTIS Annual Safety Report in addition to the standard report, both of which meet regulatory requirements from the associated agency. This feature introduces a report-level _Submission Format_ picklist for Annual Safety Report formatting that allows users to choose between the standard DSUR and the CTIS Annual Safety Report. When a user selects _CTIS Annual Safety Report_ for this field value, the generated DSUR includes unauthorized Auxiliary Medicinal Products (AxMPs) in the Interval Line Listings of Serious Adverse Reactions report and hides _Subject ID_ values in the following reports:

* Interval Line Listings of Serious Adverse Reactions
* Appendix: List of Subjects Who Died During the Reporting Period

After you have configured this feature, see <a href="/en/lr/01280/">Create DSUR Aggregate Reports</a> for more information.

## Update the Aggregate Report Object Layout

To update the _Aggregate Report_ <a href="/en/lr/26387/">object layout</a>, add the _Submission Format_ picklist field to the _Aggregate Report_ object layout after the _Datasheet_ field.

## Update the Study Product Object Layout

To update the _Study Product_ <a href="/en/lr/26387/">object layout</a>, add the _Auxiliary Medicinal Product Status_ picklist field to all _Study Product_ object layouts.

## Update the Study Product Country  Object Layout

To update the _Study Product Country_ <a href="/en/lr/26387/">object layout</a>, add the _AxMP Status Override_ picklist field to the object layout.