Learn how Vault calculates the Cumulative Dose for a Case Product.
Note: Depending on your Admin’s configuration, object, field, and section labels, lifecycle states, and workflows may differ from the general information on this page. Refer to your organization’s business processes for guidance.
About Cumulative Dose
Vault calculates the Cumulative Dose field on the Case Product when the required data points are available.
To calculate the Cumulative Dose, Vault uses the Onset field on the Case Adverse Event and the following Case Product Dosage fields:
- Dose
- Frequency
- First Admin Date
- Last Admin Date
For Vault to calculate the Cumulative Dose, the Frequency unit must match the precision of the Onset, First Admin Date and Last Admin Date.
Note: For Vault to calculate the Cumulative Dose for a monthly Dose frequency, set the Frequency to Every 30 days.
How to Trigger Cumulative Dose Auto-Calculation
When you add or update fields on the relevant Case Product Dosage or Case Adverse Event, Vault recalculates the Cumulative Dose.
Cumulative Dose Example Diagrams
The following diagrams show how Vault calculates the Cumulative Dose field using dosage intervals and the Onset date of the Case Adverse Event.
Diagram 1A: Cumulative Dose Calculation with First and Last Admin Date
- The First Admin Date and Last Admin Date are populated with a precision to the day (YYYY/MM/DD). The Onset date is also populated with a precision to the day and occurs after the Last Admin Date. Lastly, the Dose and Frequency are populated.
- Upon saving the Case Adverse Event and Case Product Dosage records, Vault calculates the Cumulative Dose.
Diagram 1B: Cumulative Dose Calculation with First and Last Admin Date (Precision to the Time)
- The First Admin Date and Last Admin Date are populated with a precision to the day (YYYY/MM/DD HH:MM). The Onset date is also populated with a precision to the time and occurs after the Last Admin Date. Lastly, the Dose and Frequency are populated.
- Upon saving the Case Adverse Event and Case Product Dosage records, Vault calculates the Cumulative Dose. The Cumulative Dose value remains the same as when using the precision to the day, however Vault calculates the Duration of the Case Product Dosage with even more precision.
Diagram 2: Cumulative Dose Calculation with Last Admin Date Past Onset Date
- The First Admin Date, Last Admin Date, and the Onset date are populated. The Last Admin Date occurs after the Onset date. The Dose and Frequency are also populated.
- Upon saving the Case Adverse Event and Case Product Dosage records, Vault calculates the Cumulative Dose. The Cumulative Dose considers the date interval until the onset of an Adverse Event. Although the Last Admin Date is July 16, the Cumulative Dose only calculates until July 11 (the Onset date).
Diagram 3: Cumulative Dose Calculation with Unknown First Admin Date
- The Last Admin Date and the Onset date are populated but the First Admin Date is blank. The Dose and Frequency are also populated.
- Upon saving the Case, Vault cannot calculate the Cumulative Dose due to an unknown First Admin Date.